2015

Cell-transfecting multilayered surfaces from poly(amido amine)s
Hujaya SD, Marchioli G, van Apeldoorn AA, Paulusse JM, Karperien M, Engbersen JF.
J Control Release. 2015 Sep 10;213:e58-9

DAMP production by human islets under low oxygen and nutrients in the presence or absence of an immunoisolating-capsule and necrostatin-1.
Paredes-Juarez G, Sahasrabudhe NM, Tjoelker RS, de Haan BJ, Engelse MA, de Koning E.J.P., Faas MM, de Vos P.
Nature Sci Reports 2015 Sep 30;5:14623.

Thirty Years of Pancreas Transplantation at Leiden University Medical Center: Long-term Follow-up in a Large Eurotransplant Center.
Kopp WH1, Verhagen MJ, Blok JJ, Huurman VA, de Fijter JW, de Koning EJ, Putter H, Baranski AG, Schaapherder AF, Braat AE, Ringers J
Transplantation. 2015 Sep;99(9):e145-51

Utilization of DCD organ donors for vascularized pancreas and islet of Langerhans transplantation: Recommendations from an expert group.
Berney T, Boffa C, Augustine T, Badet L, de Koning E, Pratschke J, Socci C, Friend P.
Transpl Int. 2015 Sep 4. doi: 10.1111/tri.12681

Controlled aggregation of primary human pancreatic islet cells leads to glucose-responsive pseudoislets comparable to native islets
Hilderink J, Spijker HS, Carlotti F, Lange L, Engelse MA, van Blitterswijk CA, de Koning EJP, Karperien M, van Apeldoorn AA.
J Cell Mol Med. 2015 Aug;19(8):1836-46.

Glycemic Stability Through Islet-After-Kidney Transplantation Using an Alemtuzumab-Based Induction Regimen and Long-Term Triple-Maintenance Immunosuppression.
Nijhoff MF, Engelse MA, Dubbeld J, Braat AE, Ringers J, Roelen DL, van Erkel AR, Spijker HS, Bouwsma H, van der Boog PJ, de Fijter JW, Rabelink TJ, de Koning EJ.
Am J Transplant. 2015 Aug 19. doi: 10.1111/ajt.13425

Loss of Beta-cell identity occurs in type 2 diabetes and is associated with islet amyloid deposits.
Spijker HS, Song H, Ellenbroek JH, Roefs MM, Engelse MA, Bos E, Koster AJ, Rabelink TJ, Hansen BC, Clark A, Carlotti F, de Koning EJ.
Diabetes. 2015 Aug;64(8):2928-38

Cell encapsulation: technical and clinical advances.
Orive G, Santos E, Poncelet D, Hernández RM, Pedraz JL, Wahlberg LU, De Vos P, Emerich D.
Trends Pharmacol Sci. 2015 Aug;36(8):537-46

Fabrication of three-dimensional bioplotted hydrogel scaffolds for islets of Langerhans transplantation.
Marchioli G, van Gurp L, van Krieken PP, Stamatialis D, Engelse M, van Blitterswijk CA, Karperien MB, de Koning E, Alblas J, Moroni L, van Apeldoorn AA.
Biofabrication. 2015 May 28;7(2):025009. doi: 10.1088/1758-5090/7/2/025009.

Circulating MicroRNAs Associate With Diabetic Nephropathy and Systemic Microvascular Damage and Normalize After Simultaneous Pancreas-Kidney Transplantation.
Bijkerk R, Duijs JM, Khairoun M, Ter Horst CJ, van der Pol P, Mallat MJ, Rotmans JI, de Vries AP, de Koning EJ, de Fijter JW, Rabelink TJ, van Zonneveld AJ, Reinders ME.
Am J Transplant. 2015 Apr;15(4):1081-90.

Poly(amido amine)-Based Multilayered Thin Films on 2D and 3D Supports for Surface-Mediated Cell Transfection.
Hujaya SD, Marchioli G, Roelofs K, van Apeldoorn AA, Moroni L, Karperien M, Paulusse JM, Engbersen JF.
J Control Release. 2015 Jan 28. pii: S0168-3659(15)00084-X

Structure-guided design of selective epac1 and epac2 agonists
Schwede F, Bertinetti D, Langerijs CN, Hadders MA, Wienk H, Ellenbroek JH, de Koning EJ, Bos JL, Herberg FW, Genieser HG, Janssen RA, Rehmann H
PLoS Biol. 2015 Jan 20;13(1):e1002038